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In another study using HCT116 and SW620 colon cancer cell lines, researchers investigated the molecular mechanism underlying curcumin's anticancer activity, with a particular focus on the miR-134-5p/CDCA3/CDK1 signaling pathway (29)

Our mapping of functional metabolic states and the underlying metabolic protein regulome further showed that elevated mTOR:AMPK phosphorylation ratio with upregulation of OXPHOS, glycolytic and fatty acid oxidation metabolism underlies the metabolic hyperactivity of the immunosuppressive phenotype of tolerogenic DC

Amantadine in Parkinson's disease

Kilgallon, M

USA 120 , e2304966120 (2023)