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Buteau from the University of Montreal in Quebec, Canada and colleagues, GLP-1 at physiological concentrations increased beta cell DNA synthesis that was independent of glucose

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As with P5, an increase in circulating GIP was seen with PX17 but not semaglutide

In the STEP 1 trial, 86% of participants lost at least 5% of their body weight, and 50% lost 15% or more
