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Smaller portions that feel manageable
Andy Cohen has revealed he took a small dose of a "revolutionary" GLP-1 weight loss drug over the summer and lost 25 pounds.
Regarding renal effects, the evidence of SGLT2is in preventing kidney failure is more abundant than for GLP-1RAs, which showed a beneficial effect on albuminuria but not on hard kidney endpoints
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The FDA has issued warnings about unapproved GLP-1 drugs circulating online - counterfeit, compounded, or mislabeled as research use only. When access to legitimate GLP-1 clinical trials is limited - by geography, logistics, or site capacity - progress slows
