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Berberine taken orally at 500-1500mg per day has modest evidence for blood sugar management and may produce 2-4 pounds of weight loss over 2-3 months

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Synthetic GLP-1 drugs each have their own modification that allows them to slip by DPP-4 or survive longer in the blood

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Intensified monitoring with detailed ultrasonography

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References WeGovy Label: accessdata.fda.gov/ JAMA Network Open Study: jamanetwork.com National Library of Medicine: pmc.ncbi.nlm.nih.gov Journal of Clinical Endocrinology & Metabolism : academic.oup.com University of Colorado Anschutz Medical Campus Study: medschool.cuanschutz.edu Health.com Study: health.com FDA Documentation: fda.gov JBMR Plus: academic.oup.com/jbmrplus Harvard University: health.harvard.edu

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