glp 1 medications for weight loss GLP-1s Loss: What You Need to Know Oral GLP-1 Medication Helps Patients

Per a March 3, 2026 FDA press announcement (FDA.gov press announcement, March 3, 2026), the FDA issued warning letters to 30 telehealth companies for making false or misleading claims about compounded GLP-1 products, including claims implying sameness with FDA-approved medications

Beyond glycaemic control, a key advantage of this combination lies in its multifaceted metabolic benefits

In contrast to previous studies, the incidence of bowel obstruction (including ileus, intussusception, volvulus, neurogenic bowel, megacolon, and other types of bowel obstruction) was not found to differ between SGLT-2 inhibitors and GLP-1RAs but tended to be nonsignificantly protective against these diagnoses (adjusted HR 0.83 [95% CI 0.69 to 1.01])

Tier 2: advanced alternatives in late-stage development These medications are not yet FDA-approved but have completed or are completing Phase 3 clinical trials

A double-blind, placebo-controlled, randomized trial of probiotics for primary prevention of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis