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Patients who were prescribed other GLP-1RAs or had bariatric surgery on or before the index event were excluded

Hence, GLP-1RAs can be utilized as an adjunct alongside metformin as a first-line treatment for type 2 DM or, in specific cases, as a preferred therapeutic agent when additional benefits for cardiovascular or renal protection are required [84]

This distinction is critical: it indicates that for most subgroups, weight remained essentially constant, isolating the effects of the topical treatment from weight fluctuation confounders

Switching Between Ozempic Injection and Ozempic/Rybelsus Tablets: Switching from Ozempic injection to Ozempic tablets: Patients taking the 0.5 mg dose of the injection may switch to the tablets

Higher protein intake enhances satiety, supports muscle preservation, and provides a thermic effect that partially compensates for the loss of GIP-mediated energy expenditure