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Blue Cross Blue Shield of Massachusetts will soon stop covering popular drugs for weight loss, like Ozempic.

Next up: glucagon-like peptide 1 receptor agonists, known colloquially (and identified here) as GLPs

The net effect is that after MBS, endogenous GLP-1 primarily acts on the brain to inhibit appetite, while only 10% of the secreted GLP-1 reaches the pancreas

They modulate central neural pathways and peripheral metabolic processes, providing cardiometabolic benefits beyond weight reduction

Glucagon-like peptide-1 receptor agonists also lead to satiety and appetite reduction through action on the brains appetite regulation centers, leading to weight loss in obese patients