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Int J Med Sci 2025

The Senescence-Associated Secretory Phenotype (SASP) One of the most impactful features of senescent cells is their acquisition of a complex secretome known as the SASP [55]

In the first step, NADPH reduces flavin partition, then flavin is oxidized and a redox-active disulfide bridge is reduced, thereby producing a thiolate anion and a cysteine

Polyunsaturated fatty acids drive lipid peroxidation during ferroptosis

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