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doi: 10.1089/cap.2009.0011

Furthermore, the NPs can be readily surface-modified with diverse organic compounds, ligands, and other agents to achieve target specificity, augmenting their efficacy
For example, Angong Niuhuang Wan inhibits the accumulation of ROS and Fe 2+ and improves mitochondrial dysfunction and BBB structural integrity by activating the PPAR/AKT/GPX4 pathway, thereby enhancing neurological function in rats with ischemic stroke and reducing cerebral infarction volume

The beads were removed by centrifugation, and the supernatant was resolved by SDS-PAGE
