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However, Hinge did effectively inhibit spine formation in neurons stimulated with 10 ng/ml HGF (Figure 13B), 10 " 12 M Nlel-AnglV ( Figure 13C) or lO "12 M Dihexa ( Figure 12D) further supporting the contention that these actions are mediated by the HGF/c- Met system
30: 72438 Miles FK, Kamath R, Dorney SF, et al
doi: 10.1016/j.esxm.2022.100562
In experimental models of glaucoma, overexpression of BDNF alleviated RGC loss after optic nerve injury and improved RGC survival, but this effect is time-limited because of downregulation of TrkB (the BDNF receptor) [75]
