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10.2 Mechanism and molecular target of cysteine and methionine The metabolism of homocysteine involves two pathways, i.e., reverse transsulfuration and transmethylation pathway, which results in its conversion into cysteine and methionine, respectively (Figure 1)

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A three-dimensional Gradient Multi echo Fast Field Echo (mFFE) sequence was used with five echoes to generate phase and magnitude mode brain images to determine susceptibility using an eight-channel SENSitivity Encoding (SENSE) volume head coil