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While more studies are needed, researchers Opie et al note that the cumulative and synergic effect of nutrients in the whole diet should be given more attention, in addition to the benefits of individual nutrients found in any single particular food

Ann Nutr Metab
Citicoline is included in the Optimal Brain supplement

Neurosurgery 6 , 19 (1980)

Pycnogenol is a compound of natural chemicals found in the bark of the European pine tree (see Pynogenol above) Serrapeptase Serrapeptase is a proteolytic enzyme (Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.) This enzyme is naturally processed and was discovered in the silkworm intestine
