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Veljaca M, Pavic Sladoljev D, Mildner B, Brajsa K, Bubenik M, Stipanicic S et al (2003) Safety, tolerability and pharmacokinetics of PL 14736, a novel agent for treatment of ulcerative colitis, in healthy male volunteers

It recommends a range of 6.5 to 9.5 for public water systems, 4.5 to 9.5 for bottled water, and states that carbonated waters may be even lower

Because these products are classified as cosmetics rather than medicines, they are not subject to the same regulatory scrutiny as licensed pharmaceutical treatments

Interface = a boundary surface that exists between two substances with different properties Liquid and solid: cup and coffee, machine and lubricant Liquid and liquid: water and oil Liquid and gas: seawater and air, soap bubbles Examples of roles of surfactants Cleaning Removing dirt Emulsification Dispersion Making unmixable things easier to mix Wetting / Penetration Makes wetting and soaking easier -Surfactants have different structures in their molecules with different properties: lipophilic groups (oil-fitting parts) and hydrophilic groups (water-fitting parts)

All participants received a treatment dosage once a week for 32 weeks