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Hu Y, Benya RV, Carroll RE, Diamond AM

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Reduced CII activity has consequences for central carbon metabolism because CII is involved in the conversion of succinate to fumarate within the TCA cycle 73

323,324 Astrocytes differentiated from pluripotent stem cells isolated from Duchenne muscular dystrophy patients (and carrying mutant DMD gene) were characterised by abnormal cytoskeleton, severely deficient glutamate uptake, and compromised K + buffering