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Description
Schueller, K., Pignitter, M
Curr Opin Nephrol Hypertens 2012;21:5526

Mechanism: Semaglutide works primarily through appetite suppression by acting on GLP-1 receptors in the brain and gut
These receptors bind ubiquitinated proteins through their UBD domains and simultaneously interact with LC3 via their LIR domains, targeting abnormal proteins for autophagic degradation

This assertion is backed by some early animal research
