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There is also some limited evidence suggesting that individuals who carry certain polymorphisms in genes involved in vitamin C transport and detoxification mechanisms may have lower plasma vitamin C concentrations even with high vitamin C intakes (see also Vascular complications of diabetes mellitus) (reviewed in 27)

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Conventional classification of these four subtypes is based on the expression of ER (estrogen receptor), PR (progesterone receptor), and HER2 (human epidermal growth factor receptor 2) (Supplementary Table 8)

Because of this, it's primarily studied and used for cognitive benefitsfocus, mental clarity, and neurological health