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The clinical role of the TME in solid cancer

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The fly brain is organized into three distinct regions, including the protocerebrum, deutocerebrum and tritocerebrum, which are analogous regions to forebrain, midbrain and hindbrain in humans (Reichert, 2005)

Increase in oxidative stress and inflammatory process resulted in renal morphological degeneration such as vascular congestion, glomerular degeneration and tubular interstitial oedema which were alleviated with melatonin (10mg/kg) co-administration