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Cultured hepatocytes were also treated with gene silencing small interfering RNAs (siRNAs) for Nrf2 , Atf4 , and Ppara

& Reddy, K

Effects of selected phytoestrogens and their mixtures on the function of the thyroid hormone and the aryl hydrocarbon receptor

GSH concentrations in tumor tissues are higher than that in the blood circulation system and normal tissues, as is reported that tumor tissues exhibits at least fourfold GSH concentration compared with normal tissues (15 mol/L), and the intracellular GSH concentration is then much higher and can reach up to 210 mmol/L (He et al

Subsequently, Nuclear Factor Erythroid 2-related Factor 2 (NRF2) was identified as a transcription factor involved in regulating gene expression at these ARE sequences (Itoh et al., 1997