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Dominant-negative G subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease

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Cellular oxidative stress causes the dissociation of the complex, oligomerization of GSTP, and induction of the JNK pathway, resulting in apoptosis

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A separate branch forms the cyclic sulfur compounds, 2-vinyl-4 H -1,3-dithiin and 3-vinyl-4 H -1,2-dithiin
