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145 Telaglenastat, a glutaminase inhibitor, was also evaluated in combination with everolimus (TelaE) in a phase I trial of advanced/metastatic renal cell carcinoma (mRCC), and TelaE therapy was well tolerated in patients previously treated with TKIs and checkpoint inhibitors (NCT03163667)

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Bolaos JP, Almeida A, Moncada S

39,95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others Data availability MS data were deposited to ProteomeXchange (PXD066142)

In vitro, OGD-induced ferroptosis was ameliorated by GSH, which restored cell proliferation, reduced oxidative stress, and upregulated ferroptosis defense factors