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Unfortunately, in the TME, the most frequent subset of DCs is immature DCs (iDCs) because cancer cells can preferentially recruit iDCs from peripheral blood vessels by releasing a number of cytokines (e.g., VEGF, -defensin, CXCL12, HGF, and CXCL8) 64,67,68,69

Include your standard operating procedure (SOP) that describes this COA validation program

Antonie Van Leeuwenhoek 111(1):526

With 42.5% of the patients, this is a significantly high prevalence

however, the effect on migration of cells persists for much longer after the clearance of the peptide from the plasma