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Upon oral intake, acetyl-l-carnitine supplements are rapidly deacetylated, i.e., converted back to l-carnitine and acetyl-CoA within the intestinal wall before absorption

Some studies have shown that it speeds up muscle recovery, while others suggest it wont do much to improve performance

For example, sugar alcohols like sorbitol and mannitol are common sweeteners that are poorly absorbed in the GI tract

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This might be due to the heterogenicity in the study materials from ME/CFS patients, different severity of the disease, prior infections and medication history of the patients