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[93], various surface modifications were made to DNase I loaded microparticles using different excipients in order to provide higher lung deposition, enzyme stability and biological activity

Acknowledgments The authors acknowledge the valuable technical assistance provided by Jiaying Li and Larissa Martins during the calf infection trial

In the AG (Figure 1B), a marked peribronchiolar inflammatory infiltrate is observed, with an increased presence of mononuclear cells and a reduction in the lumen of bronchioles and alveoli

(National Academy Press) 18

[DOI] [PubMed] [Google Scholar] 63.Tomofuji T, Sanbe T, Ekuni D, Azuma T, Irie K, Maruyama T, et al