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Research indicates that when dairy products are eliminated from the diet of affected children, levels of this autoantibody decrease, leading to a restoration of folate levels in the cerebrospinal fluid [3]

For example, the NRF2-specific activator 4-octyl itaconate significantly reduces cisplatin-induced ferroptosis by activating the NRF2/HO-1 signaling pathway (Zhang et al., 2024)

A metaanalysis involving 6,011 patients on sorafenib found hand-foot skin reactions occurred in 39%, while less common cutaneous reactions included all-grade rash or desquamation (35.4%), alopecia (25.5%), pruritus (14%), and dry skin (14.1%)