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Description
These mice subsequently develop many HFpEF-like phenotypes, including concentric LV hypertrophy with diastolic dysfunction, cardiac fibrosis, reduced exercise tolerance and pulmonary congestion, although pulmonary hypertension has not been assessed

This will last about 6-12 months when stored properly

The FDA requires manufacturers to demonstrate stability under various conditions, but these studies assume proper storage

10.1161/circheartfailure.114.001469 Circ

doi: 10.1073/pnas.1322003111 3 MuYBianCLiuRWangYShaoGLiJet al