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Description
However, once LCR was tested alone using the same dosage, but for a longer period (i.e., 24 wk), no significant effect was found

For example, 2-propyl-2-pentenoic acid (2-en-VPA), a byproduct of -oxidation, and 2-propyl-4-pentenoic acid (4-en-VPA), a byproduct of -oxidation, have been incriminated in the development of cerebral oedema and in the hepatotoxicity of VPA, respectively [1724]

Lancet Infect Dis
9 One of the most important mediators in the metabolism of valproic acid is carnitine
10.1093/cvr/cvab263 51