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Practice and theory of enzyme immunoassays
GCL is specific for the glutamyl moiety and is regulated physiologically by: (a) nonallosteric feedback competitive inhibition by GSH (K i =2.3mM) which involves binding of GSH to the glutamate and another site on the enzyme (Richman and Meister, 1975
(37552484) Standard doses of acetylcysteine may fail for patients with massive acetaminophen ingestion
In this mechanism, ligand binding to the Fas cell membrane receptor directly stimulates the binding of the initiator caspase, caspase-8 [90]
doi: 10.1016/j.neuroscience.2018.04.017 123
