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Description
However, persistent activation of Nrf2, due to Keap1 or Nrf2 gene mutations, can drive HCC pathogenesis [307]

muricata restored antioxidant enzymes, namely, SOD, CAT, GST and GSH

Villarama CD, Maibach HI

Michalopoulos GK

As a matter of fact, this protective effect is achieved through the regulation of GSH metabolic pathways, prevention of DNA damage, control of cell proliferation and survival, as well as inhibition of angiogenesis and metastasis [84,85]
