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These isogenic, mutation-specific cell lines have become a crucial tool for the pre-clinical screening and development of mutation-specific CFTR modulators (Valley et al., 2019)

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Protein expression trends across four developmental time points were analyzed using Short Time-series Expression Miner (STEM, version 1.3.13) 47 with normalized protein counts

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Figure 4 represented the true enzymatic rate obtained by subtracting the nonenzymatic rate from the total rate (non-enzymatic and enzymatic) at different concentrations of MBB

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