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Fausto, N., Campbell, J

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TRMA is also referred to as thiamine metabolism dysfunction syndrome 1 (THMD1)

In support of this theory, one paper investigated the possibility of EBV-encoded proteins existing in ME/CFS, such as BRRF1 and BLLF3, and the effects they may have (129), while BLLF3 encodes a dUTPase and is expressed in the early phase of EBV lytic replication (127), EBV (127, 130, 131), and HHV-6 (130) dUTPase proteins has been identified in ME/CFS

showed that phosphomimetic substitution (S48E) of NTD can effectively disrupt the LLPS of TDP-43 in vitro and in cells 84