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Issues such as biocompatibility and safety concerns, the complexity of manufacturing and quality control, optimization of drug delivery efficiency, understanding of nano-bio interface interactions, assessment of long-term side effects and cumulative toxicity, cost issues, the complexity of clinical trial design, and drug resistance are all challenges that must be faced in the clinical translation of nanomedicine

2023 Mar 2

This enzyme generates 5-oxoproline and releases the amino acid or peptide that is bound to glutamate

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