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10.1016/j.plaphy.2005.11.003 117 SunW.-H.DuanM.ShuD.-F.YangS.MengQ.-W

Notably, LPC (16:0), a lipid oxidation product, is elevated in FM and directly activates acid-sensing ion channel 3 (ASIC3) on nociceptors, leading to hyperalgesia in animal models (13)

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Other protocols allow short-term human organoid growth 40 or apply a more complex collagen sandwich technique in combination with the use of small molecules (CHIR and valproic acid) to maintain growth 41