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4-38A ), and those in which they contain residual material (Fig

Conversely, inhibitors targeting key enzymes or transporting proteins in the glycolytic pathway could reduce the energy supply to tumor cells and inhibit tumor growth

Although some damage to proteins, lipids, and mitochondrial DNA occurs, mitochondrial oxidative stress and mitochondrial membrane permeability transition activation are the key events in acetaminophen-induced hepatic cell necrosis [45, 46]

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