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4-38A ), and those in which they contain residual material (Fig

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Conversely, inhibitors targeting key enzymes or transporting proteins in the glycolytic pathway could reduce the energy supply to tumor cells and inhibit tumor growth

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Although some damage to proteins, lipids, and mitochondrial DNA occurs, mitochondrial oxidative stress and mitochondrial membrane permeability transition activation are the key events in acetaminophen-induced hepatic cell necrosis [45, 46]

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