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Compared to other metallic nanoparticles like gold or copper, silver offers a cost-effective and scalable option, with proven clinical safety profiles and fewer concerns related to chronic toxicity or accumulation (Swathi et al., 2025)

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The epidermis consists of distinct layers with specialized functions

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With respect to the vasculature, the activation of GPR75 by 20-HETE in vascular smooth muscle cells leads to inhibition of the large conductance calcium- and voltage-activated potassium channel (designated K Ca 1.1 and encoded by the KCNMA1 gene)