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However, we could not directly determine the functional relevance of GRIM-19 in the ability of melatonin to reduce cytotoxicity upon Cd exposure because RNAi against GRIM-19 did not significantly suppress the protective effects of melatonin against Cd exposure

In addition to inhibiting ferroptosis, the iron chelator deferasirox also improves gut microbiota dysbiosis and enhances the production of SCFAs during dextran sulfate sodium salt-induced ulcerative colitis [92]

[DOI] [PubMed] [Google Scholar] Keremi B, Lohinai Z, Komora P, et al

J Clin Oncol 35(29):JCO2017738401, 2017
