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Similar content being viewed by others Background Oxidative stress (OS) is a toxic cellular status due to the imbalance between oxidant and antioxidant mechanisms resulting from increased production of oxidants, a dysfunction in the antioxidant system, or both [1, 2]
Phase 2 combination trials reported 35-40% discontinuation rates due to GI side effects when both agents were dosed simultaneously
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Hong MKH, Macintyre G, Wedge DC, Van Loo P, Patel K, Lunke S et al
PMID: 84 AzumaKSuzukiTKobayashiKNagaharaMImaiHSugaAet al
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