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[59] Integrin signaling will phosphorylate FAK, which can then decrease GPCR G s activity

Tebentafusp is a unique TCE bispecific format named ImmTAC that links an affinity-enhanced TCR targeting the glycoprotein-100 (gp100)-human leukocyte antigen (HLA)-A02 complex expressed in melanoma cells with an anti-CD3 scFv 103

45 Nonetheless, issues of bioavailability, dosing, and targeted delivery remain major translational challenges in clinical contexts

Ferguson, G., & Bridge, W

Nevertheless, a moderate increase in HO-1 expression can enhance its protective properties by boosting its antioxidant functions (Hassannia et al., 2018)