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Potential clinical and present clinical applications of sodium thiosulfate Sodium thiosulfate (hereafter referred to as STS or thiosulfate) is an endogenous sulfur metabolite [145], which possesses antioxidant [146], anti-inflammatory [94], and antihypertensive properties [147]

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Glutathione is well known as an anti-oxidant agent, providing a major line of defense against oxidative and other forms of stress, largely as a cofactor for the glutathione peroxidase and S-transferase enzyme families (7-10)

674 Subsequent in vivo and in vitro studies have shown that mitochondria-targeted restriction endonucleases, such as Pst I, 675 ApaLI, 676 Scal, 677 and R

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