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For example, dasatinib, a senolytic agent that inhibits tyrosine kinase (TK) activity and regulates the SASP, has been shown to promote the differentiation of CD4 + T cells toward a more juvenile phenotype

Some phytomolecules may additionally alleviate insulin resistance and stimulate incretin (GLP-1/GIP) secretion, potentially enhancing their neuroprotective

Based on the important role of ferroptosis in AD pathogenesis, inhibiting ferroptosis has become a significant strategy to reduce neuronal damage in AD in preclinical studies

The cells were then incubated with the DCFH probe in a working solution for 30 min and subsequently washed with HBSS

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