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Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mtor signaling

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This oxidative stress can lead to cell and tissue damage if not properly regulated

Together, oxidative stress and excitotoxicity form a dual mechanism that underpins the neural damage caused by N 2 O exposure

Authors contributions Wrote the manuscript and prepared the figures (SR), proposed the idea for the review and critically revised the manuscript (GYW).