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Common effects (typically mild and transient): Injection site reactions: redness, minor swelling, itching Headache, particularly during the first one to two weeks Flushing or warmth sensation post-injection Mild water retention, particularly in the early weeks Drowsiness with evening doses (a GH-mediated effect) Mild increases in hunger in some individuals (less pronounced than with GHRP-6) Less common: Lightheadedness or transient dizziness Tingling or numbness in extremities (GH-mediated fluid shifts) Joint stiffness at higher doses or during extended cycles The absence of meaningful cortisol and prolactin effects is the central safety advantage of ipamorelin

Headache and joint pain

However, selenium deficiency results in premature chain termination at the UGA codon as well as in increased degradation of the selenoprotein mRNAs (14)

A.Hurtado-NedelecM.et al

doi: 10.3390/molecules21111442