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[DOI] [PMC free article] [PubMed] [Google Scholar] 383.Pritchard J.B., Miller D.S

56 These results highlight the possibility that genetic variation may have significant effects on susceptibility toward cancer

Similarly, Variability in cytokine responsiveness has also been observed in vitamin-based interventions

Existing evidence is limited to preliminary observations from small cohorts and short follow-up, which does not allow for firm clinical conclusions (216)

Since almost all tumours in LS patients are hyper-mutated, they are likely to express large numbers of neoantigens, which in turn could elicit an antigen-specific cytotoxic T-cell response 15,16,17
