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This would presumably rely on its spirosuccinimide moiety, which bears resemblance to both the glutarimide motif present in thalidomide analogs and the asparagine cyclic imide modification proposed to be a natural degron recognized by CRBN 38,39,40

Front Pharmacol 15:1516650 Jiang Y et al (2024) Endocrine and metabolic factors and the risk of idiopathic pulmonary fibrosis: a Mendelian randomization study

doi: 10.1111/acel.12888 24 CotelliM.CalabriaM.ManentiR.RosiniS.ZanettiO.CappaS

It replenishes essential vitamins (B12, B3, B6) that are often deficient in patients with anaemia, malnutrition, or chronic illness, thereby improving overall health

Randomized Phase II Trial of Two Schedules of Decitabine As Frontline Therapy in Elderly Patients with Acute Myeloid Leukemia Ineligible for Standard Cytotoxic Induction Regimens
