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BPC-157 is a compounded medication prescribed off-label

Although in vitro evaluations have high sensitivity and can be used to rule out potential herb-drug interactions, it is important to follow up positive in vitro findings with a human clinical trial to estimate the potential impact of an interaction on clinical outcomes

In a comprehensive 2018 review published in Current Neuropharmacology , Sikiric and colleagues examined the brain-gut axis interactions of BPC-157 and noted that doses ranging from as low as 10 ng/kg to 10 g/kg produced observable effects in various experimental models (PMID: 28707506)

It has been observed that serum trimethylamine N-oxide (TMAO) level, which is a microbiota-dependent metabolite, is associated with OP