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Mean weight change was approximately -2.0 kg for AOD-9604 (twice-daily) versus -1.5 kg placebo (p = not significant)
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The study concludes: Our results show that ABCD4 colocalizes with the lysosomal proteins LAMP1 and LMBD1, the latter of which is deficient in the cblF defect
A 2023 randomised study of 214 adults found only 0.9 lbs additional weight loss over three months compared to placebo not statistically significant
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