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Keywords: H2 antagonists, diabetes, neuropathy, folic acid, magnesium, microbiome Introduction Diabetes has a global impact on health, with 415 million known adult cases, of which 91% have type 2 diabetes (T2DM)

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188,191 Increased consumption of high-calorie and processed foods may increase the likelihood of anxiety disorders in childhood, adolescence, and adulthood, and animal studies have found repeated exposure to sugar-rich foods can provoke anxiety-related behavior