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On the one hand, excess iron ions can directly catalyze ROS production, exacerbating oxidative stress, while also promoting the generation and aggregation of A and catalyzing the hyperphosphorylation of the tau protein
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doi:10.12688/f1000research.23995.2 74
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Loomba R, Sanyal AJ, Nakajima A, Neuschwander-Tetri BA, Goodman ZD, Harrison SA, Lawitz EJ, Gunn N, Imajo K, Ravendhran N, et al
