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They demonstrate that urine SAM is a potent biomarker for monitoring renal function decline at early CKD stages [59]
Mechanistically, this may relate to GHK-Cu's ability to upregulate matrix metalloproteinases (MMP-1, MMP-2), enzymes that can fragment collagen if their activity exceeds the body's ability to rebuild

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Furthermore, our study uncovered a significant elevation of RBM15 expression in AD compared to normal tissues (Figure 1D)
