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M., & Ragan, M

This study revealed that mitochondrial and neuronal damage, along with iron overload and ferroptosis, occur in the hippocampus of STZ-induced type 1 diabetic rats, indicating that SLC40A1-mediated ferroptosis is linked to cognitive impairment in DM [155]

When mtROS are reduced, the cross-presentation ability of pDCs is significantly diminished, leading to a substantial decrease in their capacity to trigger CD8 + T cell responses [158]

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Support was also received via Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) Grant Number JP18dm0207001 (TCS) and a research grant from the RIKEN Center for Brain Science