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Various derived metabolites such as SCFAs, SBAs, 5-HT, Hi, and vitamins are more often indicated as signaling molecules and substrates of metabolic reactions, which affect the distal bone tissues through pathway conduction and cascade, and participate in the formation, metabolism, and maintenance of the skeleton (41)

Heeba GH, Mahmoud ME, El Hanafy AA (2014) Anti-inflammatory potential of curcumin and quercetin in rats: role of oxidative stress, heme oxygenase-1 and TNF-

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4 Antioxidant-treated rd10+/+ mice showed preservation of cone function, including a significant increase in photopic ERG b-wave amplitudes